منابع مشابه
Prions in skeletal muscle.
Considerable evidence argues that consumption of beef products from cattle infected with bovine spongiform encephalopathy (BSE) prions causes new variant Creutzfeldt-Jakob disease. In an effort to prevent new variant Creutzfeldt-Jakob disease, certain "specified offals," including neural and lymphatic tissues, thought to contain high titers of prions have been excluded from foods destined for h...
متن کاملPrions in skeletal muscles of deer with chronic wasting disease.
The emergence of chronic wasting disease (CWD) in deer and elk in an increasingly wide geographic area, as well as the interspecies transmission of bovine spongiform encephalopathy to humans in the form of variant Creutzfeldt Jakob disease, have raised concerns about the zoonotic potential of CWD. Because meat consumption is the most likely means of exposure, it is important to determine whethe...
متن کاملDisplacement in Skeletal Muscle
In skeletal muscle, the waveform of Ca 2 release under clamp depolarization exhibits an early peak. Its decay reflects an inactivation, which locally corresponds to the termination of Ca 2 sparks, and is crucial for rapid control. In cardiac muscle, both the frequency of spontaneous sparks (i.e., their activation) and their termination appear to be strongly dependent on the Ca 2 content in the ...
متن کاملATPase in skeletal muscle
1. Abstract 2. Introduction 3. Materials and Methods 3.1. Experimental set-up 3.2. External (superfusion) solutions 3.2. Internal (perfusion) solutions 3.3. Measurement of pHi 3.4. Measurement of the intracellular pH buffering power 3.5. Measurement of tracer efflux 3.6. Determination of the stoichiometry of Ca /H exchange 3.7. Voltage-clamping of Barnacle muscle cells 3.8. Reagents 3.9. Statis...
متن کاملRelease in Skeletal Muscle
Amplitude, spatial width, and rise time of Ca 2 1 sparks were compared in frog fast-twitch muscle, in three conditions that alter activation of release channels by [Ca 2 1 ]. A total of z 17,000 sparks from 30 cells were evaluated. In cells under voltage clamp, caffeine (0.5 or 1 mM) increased average spark width by 28%, rise time by 18%, and amplitude by 7%. Increases in width were significant...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.052707499